Opioid Conversion ChartOpioid Conversion Chart
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OPIOID CONVERSION CHART
There are differences in the literature regarding opioid conversion ratios. The conversion ratios listed below are the conversion ratios commonly used in practice at Our Lady’s Hospice and
Care Services (OLH&CS). The information outlined below is intended as a guide only. All medication doses derived using the information below should be checked and prescribed by an
experienced practitioner. The dosage of a new opioid is based on several factors including the available equi-analgesic dose data, the clinical condition of the patient, concurrent
medications and patient safety. It is recommended that the new dose should be reduced by 30-50% to allow for incomplete cross-tolerance. The patient should be monitored closely until
stable when switching opioid medications.

GOLDEN RULE: WHEN CHANGING FROM ONE OPIOID TO ANOTHER ALWAYS CONVERT TO MORPHINE FIRST.
ORAL MORPHINE TO ORAL OPIOIDS

ORAL OPIOIDS TO PARENTERAL OPIOIDS

PO → PO

RATIO

Morphine → Oxycodone

1.5:1