Opioid Analgesic Conversion Chart
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Opioid

IV (mg)

PO
(mg)

3–4

Morphine (MSIR)
10

30

Morphine SR
(MS Contin®,
Kadian®, Avinza®)
Hydromorphone
(Dilaudid)

1.5

7.5

Fentanyl inj.
(Sublimaze)
Fentanyl tab/loz.
(Actiq, Fentora,
Onsolis, Abstral)
Fentanyl patch
(Duragesic)
Methadone

OPIOID ANALGESIC CONVERSION CHART
Interval/
Onset
Peak
Duration
(min)
(min)
(hr)

0.1–0.2

0.2–0.4

See comments

IM 15–30
IV < 5 PO 15–60 PR 10–20 SC 5–10Comments30–60 10–20 60 20–60 50–90Injection: 2,4,8,10,15 mg/mL syringes Oral IR: 10,15,30 mg tablets Oral soln: 10mg/5mL, 20mg/mL Suppositories: 5,10,20,30 mg60MS Contin (q12h): 15,30,60,100,200 mg tabs, Kadian (q12h): 20,30,50,60,80,100 mg caps, Avinza (q24h):30,60,90,120 mg caps8–1220 – 403–4IM 15–30, IV < 5, PO 15–30IV: 0.5–1 PO: 1–2IV 1–2Buccal: 1–2Buccal 5–15728 – 12 hr24 – 36 hr25mcg patch = 60mg oral morphine/day Patches: 12, 25, 50, 75, 100 mcg/hr6-12